PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
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Conditions studied: Lumbar Disc Herniation, Lumbar Radiculopathy
In brief
This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD). In routine clinical practice, some patients receive an additional transforaminal anterior epidural steroid injection during the same session without an extra puncture. This study will prospectively follow patients who receive PLDD alone and those who receive PLDD combined with epidural steroid injection. Pain intensity, functional status, analgesic use, need for additional interventions, and complications will be assessed over time. The results may help to clarify whether adding epidural steroid injection to PLDD improves clinical outcomes in patients with lumbar disc herniation.
Key facts
- Study ID
- NCT07400068
- Run by
- Mersin University
- People needed
- 88
- Starts
- 2026-03-01
- Expected to finish
- 2027-09-01
- Last updated by the study team
- 2026-02-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 years and older
- Diagnosis of single-level lumbar disc herniation confirmed by magnetic resonance imaging (MRI)
- Presence of radicular leg pain refractory to conservative treatment
- Undergoing routine percutaneous laser disc decompression (PLDD) as part of standard clinical care
- Ability to provide informed consent
You may not qualify if…
- Multilevel lumbar disc herniation
- Extruded or sequestered disc herniation
- Severe spinal canal stenosis or spinal instability
- Previous lumbar spine surgery at the affected level
- Active infection or systemic inflammatory disease
- Coagulopathy or use of anticoagulant therapy contraindicating intervention
- Pregnancy
- Inability to complete follow-up assessments
Where it is running
- Mersin University Faculty of Medicine, Department of Algology — Mersin, Yenişehir, Turkey (Türkiye)
Full record on ClinicalTrials.gov
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