A Comparative Evaluation of the Role of Self-Adhesive Flowable Composite in Enhancing Sealant Retention Versus Conventional Pits and Fissure Sealant With and Without Fissurotomy in Permanent Molars
Starting soon · Not applicable
Conditions studied: Pits and Fissure Sealants
In brief
This RCT study aims to establish evidence-based decision comparing between self-adhering flowable composite Vertise™ Flow (Kerr, Orange, CA, USA) and conventional resin-based pits \& fissure sealant Helioseal-F sealant (Ivoclar Vivadent AG, Schaan, Liechtenstein) with and without fissurotomy in sealant retention and prevention of occlusal pits and fissures caries in first permanent molars over a 12-month follow-up.
Key facts
- Study ID
- NCT07399340
- Run by
- Cairo University
- People needed
- 88
- Starts
- 2026-03-01
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-02-10
Who can join
Age: 6 and older, up to 8. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Normal healthy children aged 6 to 8 years.
- Children with high caries risk
- Completely erupted lower first permanent molars with deep pits and fissures.
- Fissures either intact, sound or retentive which are stained, caries free or ICDAS 0-2.
- Availability for the duration of the study.
- Satisfactory dental care performed at home.
You may not qualify if…
- Children whose parents refuse to sign informed consent.
- Long-term medication affecting the salivary flow.
- Children enrolled for other studies or fluoridation program.
- Adverse reaction reported to any dental material.
- Uncooperative child.
- Bruxism or malocclusion.
- Children with developmental defects/ hypoplastic molars or caries affected teeth (ICDAS>2).
- Teeth with restoration and partially retained sealants.
- Children who cannot come for the follow-up.
Where it is running
- Faculty of Dentistry, Cairo University — Cairo, State/Province *, Egypt
- Faculty of Dentistry, Cairo University — Cairo, State/Province *, Egypt
Full record on ClinicalTrials.gov
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