Multimodal Training Effects in Middle-Aged and Older Adults With Diabetic Sarcopenia

Recruiting now · Not applicable

Conditions studied: Type 2 Diabetes Mellitus (T2DM), Sarcopenia

In brief

This study aims to investigate the effects of a 12-week multimodal exercise intervention on middle-aged and older adults (aged 45\~85 years) with Type 2 Diabetes Mellitus (T2DM). The program combines supervised training, home-based sessions, and digital support to improve muscle function, physical performance, metabolic control, and quality of life.

Key facts

Study ID

NCT07398495

Run by

yueh chu wu

People needed

128

Starts

2026-02-23

Expected to finish

2026-08-15

Last updated by the study team

2026-03-30

Who can join

Age: 45 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with both Type 2 Diabetes Mellitus (T2DM) and sarcopenia.
• Maintained on a stable regimen of oral hypoglycemic agents.
• Aged 45 years or older.
• Capable of communicating effectively in Mandarin or Taiwanese.
• Willing to provide informed consent or have it obtained from a legally authorized representative.

You may not qualify if…

• • Limited limb or joint function that prevents exercise (e.g., recent fractures or dislocations).
• Communication barriers or severe emotional/psychological issues (e.g., uncontrolled depression or severe mental illness).
• Severe cognitive impairment (e.g., dementia).
• End-stage renal disease (ESRD).
• Major comorbidities or complications, including active diabetic foot ulcers, amputation, recent myocardial infarction, severe autonomic neuropathy, or a history of stroke within the last 3 years.

Where it is running

• Chung Shan Medical University Hospital — Taichung, Taiwan, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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