Intracranial EEG to Test How Noninvasive Stimulation Affects Hippocampal-dependent Memory

Enrolling by invitation · Not applicable

Conditions studied: Memory Performance, Hippocampal Network Activity

In brief

Human intracranial electroencephalography (EEG) can provide brain-activity correlates of memory with high spatial and temporal resolution. This project will test functional relevance of these neural signals for memory behavioral performance using a novel noninvasive stimulation method. Findings will advance understanding of brain mechanisms for memory, as is needed to accelerate progress in the treatment of memory disorders.

Key facts

Study ID

NCT07397897

Run by

University of Chicago

People needed

12

Starts

2025-09-15

Expected to finish

2028-06-30

Last updated by the study team

2026-02-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18+ years old
• Native English speakers
• Normal or corrected-to-normal near and far vision

You may not qualify if…

• iEEG electrode placement in area of parietal lobe that will interfere with placement of TMS coil for HITS stimulation

Where it is running

• University of Chicago Medical Center — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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