Ultrasound-Based Prediction of Hemodynamic Instability During CVVHDF Initiation

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Conditions studied: Renal Failure , Chronic, Intradialytic Hypotension, Critical Illness

In brief

This prospective observational study aims to evaluate the ability of transthoracic echocardiographic and bedside ultrasonographic parameters to predict intradialytic hypotension and hemodynamic instability at the initiation of continuous venovenous hemodiafiltration (CVVHDF) in adult intensive care unit patients.

Key facts

Study ID

NCT07397663

Run by

Bursa Yuksek Ihtisas Training and Research Hospital

People needed

80

Starts

2026-02-10

Expected to finish

2027-02-10

Last updated by the study team

2026-02-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (≥18 years) admitted to the intensive care unit
• Indication for continuous venovenous hemodiafiltration
• Adequate transthoracic echocardiographic image quality
• Written informed consent obtained from legal representatives

You may not qualify if…

• Acute coronary syndrome
• Severe valvular heart disease or pericardial effusion
• Significant arrhythmias interfering with Doppler measurements
• Presence of pacemaker, ICD, or ventricular assist device
• Poor echocardiographic imaging window
• Life expectancy less than 24 hours

Full record on ClinicalTrials.gov

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