prTMS as an Intervention for Bradykinesia in Parkinson's Disease
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Bradykinesia, Parkinson Disease
In brief
This study investigates the use of patterned repetitive transcranial magnetic stimulation (prTMS) as an intervention for bradykinesia in Parkinson's Disease (PD). More specifically, the study aims to determine whether prTMS over the supplementary motor area (SMA) can reduce severity of bradykinesia in PD patients. This approach may open for more targeted and effective treatment of bradykinesia in PD.
Key facts
- Study ID
- NCT07397377
- Run by
- Danish Research Centre for Magnetic Resonance
- People needed
- 27
- Starts
- 2025-12-16
- Expected to finish
- 2027-05-01
- Last updated by the study team
- 2026-02-09
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Above 18 years of age. Clinically established or probable Parkinson's Disease (PD), according to the Movement Disorder Society.
- Clinical Diagnostic Criteria for PD. Stable antiparkinsonian medicine for at least four weeks. Signed informed consent.
You may not qualify if…
- Psychiatric disorders. Current use of antipsychotic medication, Donepezil, or GABAergic agents (e.g., pregabalin, gabapentin).
- Frequent benzodiazepine or opioid use defined as more than once per week on a regular basis.
- History of neurological disease other than PD. Past or present mental illness. History of epilepsy/conditions associated with increased risk of seizure induction through transcranial magnetic stimulation (TMS).
- Close relatives suffering from epilepsy/conditions associated with increased risk of seizures.
- Contraindications for magnetic resonance imaging (MRI) Contraindications for TMS Female participants of childbearing age must not be pregnant and must use contraception during the trial.
- Refuse to be informed about new health-related information and accidental health-related findings that might appear through participation in the study.
Where it is running
- DRCMR — Hvidovre, Denmark (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.