Thyroid Cartilage Plane VS Superior Laryngeal Nerve Space Block in Awake Tracheal Intubation

Recruiting now · Not applicable

Conditions studied: Superior Laryngeal Nerve Block

In brief

The aim of this clinical trial is to compare the effectiveness and safety of ultrasound-guided thyroid cartilage plane approach with the superior laryngeal nerve space approach for superior laryngeal nerve block in awake tracheal intubation. Patients were randomized into the thyroid cartilage plane block group (T group) or the superior laryngeal nerve space block group (C group). In Group T, bilateral thyroid cartilage plane block was performed under ultrasound with thyroid cartilage as the landmark, and local anesthetic was injected on the surface of the thyroid cartilage. In Group C, local anesthetic was injected into the space between the thyrohyoid membrane and muscle groups above. The investigators aim to evaluate whether the thyroid cartilage plane approach is not inferior to the superior laryngeal nerve space approach for ultrasound-guided superior laryngeal nerve block in awake tracheal intubation

Key facts

Study ID

NCT07397234

Run by

Nanjing First Hospital, Nanjing Medical University

People needed

94

Starts

2026-02-11

Expected to finish

2027-09-01

Last updated by the study team

2026-07-28

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients scheduled for awake tracheal intubation under general anesthesia.
• Patients with difficult airways (e.g., limited cervical spine mobility, full stomach, partial airway obstruction, craniofacial deformities or trauma, micrognathia, mouth opening <3cm, Mallampati III or IV classification) posing challenges for mask ventilation or intubation.
• Age between 18 and 85 years old.
• Gender is not restricted.
• ASA classification of I - III.

You may not qualify if…

• Cardiovascular dysfunction or arterial aneurysms.
• Mental or neurological disorders or concomitant arterial aneurysms.
• Infection at the puncture site.
• Allergy to local anesthetics.
• Continuous use of antiplatelet or anticoagulant medications preoperatively.
• Hoarseness or coughing while drinking water.
• Bronchial asthma.
• Participation in other clinical trials within the previous 3 months before enrollment 9.r current participation in other clinical trials.

Where it is running

• Nanjing First Hospital — Nanjing, China (enrolling)
• Nanjing First Hospital — Nanjing, Jiangsu, China

Full record on ClinicalTrials.gov

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