Assessment of the Repeatability of Sublingual Microcirculation Function Measurements in Healthy Volunteers and Critically Ill Patients

Starting soon

Conditions studied: Critical Illness, Healthy

In brief

The assessment of microcirculatory function plays a pivotal role in perioperative medicine and intensive care. One promising method for evaluating microcirculatory function is the microscopic analysis of the oral mucosal microvasculature. However, this method is not currently fully validated. The aim of this study is to assess the repeatability of sublingual microcirculation measurements using the CytoCam-IDF device (Braedius Medical).

Key facts

Study ID

NCT07397208

Run by

Medical University of Gdansk

People needed

200

Starts

2026-02-07

Expected to finish

2029-02-01

Last updated by the study team

2026-02-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• ASA Physical Status I-II
• Age 18-40 years

You may not qualify if…

• Chronic diseases
• Chronic medication use
• Pregnancy
• Use of stimulants (caffeine, nicotine, alcohol) within 12 hours prior to the study
• Lack of consent to participate
• Group 2: Patients Hospitalized in the ICU
• Inclusion Criteria:
• Age > 18 years
• Hospitalization in the Intensive Care Unit (ICU)
• Requirement for vasoactive drugs (minimum norepinephrine equivalent dose >0.1μg/kg / min )
• Mechanical ventilation via an endotracheal tube
• Exclusion Criteria:
• Head and craniofacial trauma
• Pregnancy
• Intensive fluid therapy (>200ml/h)
• Changes in vasoactive drug dosages within 30 minutes prior to study inclusion
• Hypothermia (body temperature <35.5 oC)
• Fever (body temperature >38.5oC)

Where it is running

• Medical University of Gdanks — Gdansk, Poland

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.