ACT for Veterans With IBD and Mental Health Challenges

Starting soon · Not applicable

Conditions studied: Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis, Depressive Disorder, Anxiety Disorder, Stress Disorders, Post-Traumatic

In brief

Many Veterans with gastrointestinal disorders, such as inflammatory bowel disease (IBD), also have mental health conditions. IBD and mental health conditions can worsen one another through the brain-gut axis, leading to dramatic deficits in psychosocial functioning and quality of life (QOL). Yet, few Veterans with comorbid IBD and mental health conditions receive psychotherapy and no evidence-based psychotherapies have been tested in Veterans with these comorbidities. Adapting brief acceptance and commitment therapy (ACT) to the specific to the needs of these patients and embedding treatment into routine gastroenterology care may increase Veterans' access to efficient and effective rehabilitative care. This study aims to adapt and test an integrated, 1-Day ACT intervention tailored to the specific needs of Veterans with IBD and mental health conditions to improve psychosocial functioning and QOL.

Key facts

Study ID

NCT07397195

Run by

VA Office of Research and Development

People needed

50

Starts

2028-01-01

Expected to finish

2032-06-30

Last updated by the study team

2026-02-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of IBD as confirmed by the medical record
• Current diagnosis of a depressive, anxiety, or trauma-related disorder

You may not qualify if…

• Severe IBD symptoms that would prevent full participation in the study (i.e., hospitalized in the past 30 days, surgery in the past 30 days)
• Significant cognitive impairment
• Active suicidality
• Uncontrolled psychosis or bipolar disorder

Where it is running

• Michael E. DeBakey VA Medical Center, Houston, TX — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.