Using Routine Inflammatory and Metabolic Blood Tests (Bedside Included) to Predict Brain Injury in Children After Minor Head Trauma
Starting soon
Conditions studied: Brain Injury Traumatic Mild
In brief
Traumatic brain injury (TBI) poses significant strains on the paediatric population, for which the possible side effects of diagnostic imagistics could induce life-altering conditions. Routine inflammatory and metabolic biomarkers (complete blood count, C reactive protein, glucose) are frequently sampled in the paediatric patients admited within emergency departments, including the low-resource settings. This study aims to retrospectively document whether such routine blood biomarkers could predict a positive head CT scan and subsequently contribute to a prediction score, ment to enable more accurate decision on which minor TBI paediatric patients should be submitted to diagnotic imagistics.
Key facts
- Study ID
- NCT07397091
- Run by
- Iuliu Hatieganu University of Medicine and Pharmacy
- People needed
- 800
- Starts
- 2026-04-20
- Expected to finish
- 2026-06-20
- Last updated by the study team
- 2026-03-31
Who can join
Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged 0 to 18 years old presenting to the ED with mild traumatic brain injury (with or without cervical injury):
- Mild TBI will be defined as GCS 14-15 or A (AVPU) upon admission
- Patients underwent head CT
- Routine blood biomarkers have been collected (complete blood count - CBC, biochemistry and/or (arterial) venos blood gases - (A)VBG).
You may not qualify if…
- Patients with moderate (GCS 13-9 or V) or severe (GCS 8-3 or P,U) head trauma
- Patients with associated trauma (limb/rib/pelvic fractures, organ injuries).
Where it is running
- Spitalul Clinic Judetean de Urgenta — Arad, Romania
- Spitalul Judetean de Urgenta — Baia Mare, Romania
- Spitalul Clinic Judetean de Urgenta — Bistriţa, Romania
- Spitalul Judetean de Urgenta MAVROMATI — Botoșani, Romania
- Spitalul Clinic de Urgenta penru Copii — Brasov, Romania
- Spitalul Clinic de Urgenta pentru Copii — Cluj-Napoca, Romania
- Spitalul Clinic Judetean de Urgenta — Craiova, Romania
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.