Ankylosing Spondylitis
Starting soon
Conditions studied: Ankylosing Spondylitis
In brief
The goal of this observational study is to measure the serum level of cytokines IL-17, IL-38,IL-41, and gene expression of HLA-B27 gene in ankylosing spondylitis patients and healthy control group. The main question it aims to answer is: Does the disease activity, severity, serum level of cytokines (IL-17, IL-38, and IL-41) are affected by the HLA-b27 gene positivity? Researchers will compare the serum level of cytokines IL-17, IL-38,IL-41, and gene expression of HLA-B27 gene in ankylosing spondylitis patients and healthy control group to see if there significant differences in serum levels of interleukins 17, 38, 41 in AS patients and healthy control group. .
Key facts
- Study ID
- NCT07396194
- Run by
- Sohag University
- People needed
- 84
- Starts
- 2026-03-01
- Expected to finish
- 2027-03-01
- Last updated by the study team
- 2026-02-09
Who can join
Age: 16 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- patients who are diagnosed clinically as ankylosing spondylitis (both active or stable), of either sex , who met the Assessment of Spondyloarthritis International Society (ASAS) criteria for axial spondyloarthritis.
You may not qualify if…
- Patients with any autoimmune disorder, chronic illnesses as diabetes mellitus, acute and chronic infectious diseases, malignancy.
Full record on ClinicalTrials.gov
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