Assessments of Obsessive-compulsive Symptoms in Patients With Substances Use Disorder
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Conditions studied: Obsessive - Compulsive Disorder, Obsessive Compulsive Disorder (OCD), Obsessive Compulsive Behavior, Substance Abuse Disorder, Substance Use
In brief
This observational, cross-sectional case-control study evaluates obsessive-compulsive symptoms among adults with substance use disorder compared with a demographically similar control group without substance use disorder. Patients aged 18-50 years attending the addiction management inpatient and outpatient services at Assiut University Hospital, and healthy controls recruited from relatives, friends, and hospital staff, will complete structured clinical interviews, the Yale-Brown Obsessive-Compulsive Scale, and other standardized scales for psychiatric symptoms, cognition, and quality of life. The main objective is to estimate the prevalence and severity of obsessive-compulsive symptoms in substance use disorder and examine their associations with sociodemographic and clinical factors, addiction severity, and quality of life in the recovery stage.
Key facts
- Study ID
- NCT07395453
- Run by
- Assiut University
- People needed
- 102
- Starts
- 2026-03-01
- Expected to finish
- 2027-04-01
- Last updated by the study team
- 2026-02-09
Who can join
Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- -Adults aged 18-50 years.
- Willing and able to provide informed consent and participate in the study assessments.
- For the case group: patients with a diagnosed substance use disorder (single or polysubstance) attending the inpatient or outpatient addiction management unit at the Neuropsychiatry Department, Assiut University Hospital.
- For the control group: relatives, friends, or hospital workers without substance use disorder, recruited through invitation or advertisement.
You may not qualify if…
- Severe psychiatric comorbidities such as schizophrenia, major depressive disorder, bipolar disorder, or anorexia nervosa.
- Current intoxication or acute withdrawal state from substances.
- Severe medical conditions including end-stage renal disease, metastatic cancer, severe heart failure, or chronic obstructive pulmonary disease.
- Severe cognitive impairment
Full record on ClinicalTrials.gov
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