The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults

Starting soon · Not applicable

Conditions studied: Kidney Stones, Urine Specimen Collection

In brief

This is a single-center prospective cohort study to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.

Key facts

Study ID

NCT07389226

Run by

University of Chicago

People needed

30

Starts

2026-12-01

Expected to finish

2028-02-01

Last updated by the study team

2026-07-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Controls: Adults above the age of 18.
• Kidney stone patients: Adults above the age of 18.
• History of majority (>50%) calcium oxalate kidney stones

You may not qualify if…

• Anyone with a history of calcium phosphate stones (>50% calcium phosphate), uric acid stones, struvite stones, recent urinary tract instrumentation (<30 days), or recurrent urinary tract infections.
• Any individual who has had ACV outside of normal consumption in the prior month will be excluded.
• Any individual who has a history of a negative reaction (increased acid reflux, allergy) to ACV will also be excluded.
• Any individual with chronic kidney disease, underlying acid base disorder will also be excluded.

Where it is running

• The University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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