Soluble and Osmotic Fibre (SOLOS) Diet for Constipation
Starting soon
Conditions studied: Constipation, Constipation - Functional, Constipation Chronic Idiopathic, Constipation Predominant Irritable Bowel Syndrome, Constipation, Signs and Symptoms, Digestive, Constipation-predominant IBS (IBS-C), Constipation-predominant Irritable Bowel Syndrome, Constipation-predominant Irritable Bowel Syndrome (IBS-C), Diet Therapy, Diet Modification, Diet, Food and Nutrition, Dietary and Nutritional Therapies, Dietary Fiber, Dietary Fibers
In brief
This research aims to study the dual effectiveness of incorporating soluble fibre and osmotic carbohydrates (SOLOS), with or without restricting fructans and GOS, and present novel findings in managing GI symptoms in patients with functional bowel disorders with constipation. These findings may also support researchers and clinicians in shaping new dietary approaches in the management of general constipation symptoms.
Key facts
- Study ID
- NCT07388589
- Run by
- Singapore Institute of Technology
- People needed
- 180
- Starts
- 2026-02-02
- Expected to finish
- 2027-03-01
- Last updated by the study team
- 2026-02-06
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Presented with symptoms of FC, IBS-C, or SIBO-C
- Were aged 18 to 70 years old. (Research focus is on adult patients, excluding older adults and children)
- Date of baseline (first) and follow-up appointments ranged from January 2021 to December 2025
- Did not attend follow-up appointments (Data would be treated as "intention to treat" and data points were carried forward for conservative analysis).
You may not qualify if…
- Had no history of constipation-related symptoms (Does not relate to research question's population or outcome)
- Started treatment before January 2021
- Were not due for follow-up before the end of December 2025
- Symptom and stool data inadequately recorded
Where it is running
- Singapore Institute of Technology — Singapore, Singapore, Singapore
Full record on ClinicalTrials.gov
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