The Effect of Centralization on Medial Meniscal Extrusion for Medial Meniscus Posterior Root Tear Repair
Enrolling by invitation · Not applicable
Conditions studied: Meniscus Tear
In brief
The purpose of this research is to determine if meniscus root repair with or without centralization will have an impact on postoperative pain, function, activity levels, patient satisfaction, and incidence of revision meniscus surgery.
Key facts
- Study ID
- NCT07388290
- Run by
- Mayo Clinic
- People needed
- 54
- Starts
- 2026-02-17
- Expected to finish
- 2030-03-01
- Last updated by the study team
- 2026-04-13
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Type 2 Medial Meniscus Posterior Root Tear demonstrated on MRI
- Notable extrusion (>3 mm) on preoperative MRI
- Patient able to consent for themselves
- Patient agrees to comply with trial schedules and plan
- Pre-operative Exclusion:
- Concomitant ligamentous or meniscal procedures
- Meniscal extrusion > 6 mm on pre-operative MRI
- Kellgren-Lawrence grade > 2
- Varus malalignment > 10 degrees
- Asymmetric varus alignment > 5 degrees
- Varus thrust while weightbearing
- Grade 3 bipolar medial compartment changes (isolated grade 3 changes on single articular surface with ≤ grade 2 changes on the opposing surface remains eligible)
- Previous surgery of the affected knee
- Associated fractures requiring surgery
- Concurrent Vascular injuries
- Hypermobility/Ehlers-Danlos Syndrome
- Inflammatory or autoimmune disease
- Severe mental/physical disability precluding post operative rehabilitation demands
- Contraindications to MRI
- Pregnant women
- Arthroscopy Inclusion Criteria:
- Complete radial tears within 9 mm of medial meniscus posterior root
- ICRS Grade 3 or better
- Arthroscopy Exclusion Criteria:
- Requiring concomitant procedures other than MMPRT
Where it is running
- The Steadman Clinic — West Vail, Colorado, United States
- Hospital for Special Surgery at Naples Comprehensive Health (HSS at NCH), — Naples, Florida, United States
- Mayo Clinic — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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