Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy

Recruiting now · Not applicable

Conditions studied: Early Stage Breast Carcinoma, Dyspnea

In brief

This clinical trial studies whether breathing exercises for the muscles that help with breathing air in, inspiratory muscle training (IMT), works to improve breathing muscle strength, shortness of breath, and physical activity levels in women who are receiving chemotherapy for early-stage breast cancer (BC). Cancer and/or treatments for BC can directly result in muscle wasting that involves breathing muscles, skeletal muscles or heart muscles. Pain, weakness, shortness of breath, and side effects of cancer treatment may lead to lower physical activity levels. IMT involves breathing exercises using a small hand-held device. The device makes it a little harder to breathe in, which may help strengthen breathing muscles. IMT may be an effective way to improve breathing muscle strength, shortness of breath, and physical activity levels in women who are receiving chemotherapy for early-stage BC.

Key facts

Study ID

NCT07386444

Run by

Ohio State University Comprehensive Cancer Center

People needed

58

Starts

2026-02-16

Expected to finish

2026-12-31

Last updated by the study team

2026-04-06

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Within 3 weeks of starting chemotherapy for an early-stage breast cancer diagnosis
• Able to exercise independently without needing support
• Ability to read, speak, understand English

You may not qualify if…

• Metastatic breast cancer
• Unwilling or unable to follow protocol requirements
• Any significant health condition which in the investigator's opinion increases the risks of participation or makes the participant unsuitable for the study

Where it is running

• Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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