The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma

Starting soon

Conditions studied: Endometriosis, Deep Endometriosis, Bowel Endometriosis, Colorectal Carcinoma, Colon Resection, Endometriosis Pelvic, Endometriosis Rectum, Carcinogenesis, Genetic Change, Infertility

In brief

The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma. The study will include patients for whom surgical treatment of bowel endometriosis is clinically indicated. This research would represent a significant advancement in evaluating the necessity of surgical intervention in asymptomatic patients or those with mild symptoms. Furthermore, it would provide a broader insight into the systemic impact of endometriosis on other organ systems, ultimately improving risk assessment and preventive measures.

Key facts

Study ID

NCT07386431

Run by

University Medical Centre Ljubljana

People needed

30

Starts

2026-02-01

Expected to finish

2029-05-01

Last updated by the study team

2026-02-06

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Female patients aged 18 and over, treated at the Department of Reproduction for diagnosed deep endometriosis, including bowel endometriosis, for whom surgical treatment is indicated.

You may not qualify if…

• Patients with known inflammatory bowel disease (IBD), patients with a personal history of gynecological or gastrointestinal malignancy

Full record on ClinicalTrials.gov

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