MRI Volumetry and Diffusion Tensor Imaging in Temporal Lobe Epilepsy

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Conditions studied: Temporal Lobe Epilepsy (TLE)

In brief

This works aims at evaluating the diagnostic performance of combined MRI Volumetry, Diffusion tensor imaging and Conventional MRI in lateralizing the epileptogenic focus in patients with temporal lobe epilepsy and correlate these findings with clinical outcome.

Key facts

Study ID

NCT07384351

Run by

Assiut University

People needed

78

Starts

2026-04-01

Expected to finish

2028-06-30

Last updated by the study team

2026-02-03

Who can join

Age: 12 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients with different age groups having temporal lobe epilepsy diagnosed by EEG with no detected structural brain lesion by conventional MRI other than mesial temporal sclerosis.

You may not qualify if…

• Contraindications for MRI as claustrophobia, cardiac pacemaker and non-compatible metallic devices.
• Patients with suboptimal images or techniques.
• Post-operative and post-head traumatic cases.

Full record on ClinicalTrials.gov

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