Metabolic Characteristics of Plasma OxPLs in STEMI Patients.

Enrolling by invitation

Conditions studied: STEMI - ST-segment Elevation Myocardial Infarction

In brief

The goal of this observational study is to investigate the structural composition and metabolic characteristics of OxPLs in STEMI patients. Explore OxPLs characteristic fingerprint biomarkers from different populations and analyze OxPLs fingerprint spectra. Based on the OxPLs fingerprint of STEMI patients, a machine learning classifier is used to establish an artificial intelligence assisted post PCI MACE risk prediction system, achieving the transformation of basic research into clinical application.

Key facts

Study ID

NCT07382700

Run by

First Affiliated Hospital of Ningbo University

People needed

240

Starts

2025-01-01

Expected to finish

2027-12-31

Last updated by the study team

2026-02-03

Who can join

Age: 50 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The patient meets the diagnostic criteria for STEMI (refer to the "Diagnosis and Treatment Guidelines for Acute ST Segment Elevation Myocardial Infarction (2021)")
• Agree to perform direct PCI
• The onset time is less than 12 hours and successfully undergoing emergency PCI treatment
• After admission, all STEMI patients are routinely treated with antiplatelet aggregation, anticoagulation, lipid-lowering, and anti myocardial remodeling drugs.

You may not qualify if…

• Previous history of myocardial infarction
• Accompanied by other cardiovascular diseases, such as severe heart valve disease, severe heart failure, congenital heart disease, cardiomyopathy, etc
• Merge with severe infection
• Merge with severe anemia
• Merge with severe liver and kidney dysfunction
• Combined with malignant tumors
• Accompanied by a history of autoimmune or hematological diseases
• Recent history of severe trauma or surgery
• Patients with incomplete clinical data
• The patient does not agree to undergo data collection

Where it is running

• First Affiliated Hospital of Ningbo University — Ningbo, Zhejiang, China

Full record on ClinicalTrials.gov

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