Zesty Exercise System for Therapeutic Engagement
Recruiting now · Not applicable
Conditions studied: Parkinson Disease
In brief
This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely. Participants will complete robot-guided exercise three times per week for three weeks. The study will assess feasibility, retention, safety, acceptability, and tolerability of remotely monitored ZEST-E and will measure changes in functional performance using the Standing Forward Reach test and the 30-Second Chair Stand test. These outcomes reflect range of motion and lower-body strength targeted by the exercise program.
Key facts
- Study ID
- NCT07382674
- Run by
- Emory University
- People needed
- 46
- Starts
- 2026-03-16
- Expected to finish
- 2028-02-01
- Last updated by the study team
- 2026-05-26
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Older adults with mild to moderate PD.
You may not qualify if…
- Acute medical illness requiring hospitalization;
- Under 40 years old;
- Uncontrolled congestive heart failure;
- History of stroke in the past three years;
- Inability to perform study procedures;
- Medical or physical conditions that would preclude participation (e.g., severe arthritis or mobility problems, uncontrolled hypertension or diabetes, renal failure, history of angina with activity);
- On medications that could adversely affect cognition, e.g.: antipsychotics, opioids, stimulants, chemotherapy;
- Psychotic disorders;
- Confounding neurologic conditions (e.g., active central nervous system opportunistic infections, seizure disorders, head injury with loss of consciousness >30 minutes, intracranial neoplasms, stroke with neurological or neuropsychiatric sequelae);
- Substance Use Disorder, Major Depressive and Generalized Anxiety Disorders within six months of evaluation;
- Hohn \& Yahr > 3
- MoCA <17
Where it is running
- Emory University, 57 Executive Park S NE, Ste 200 — Atlanta, Georgia, United States (enrolling)
Full record on ClinicalTrials.gov
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