Early Identification of Cardivascular Damage Induced by Chemotherapy and Antineoplastic Treatments in Pediatric Age

Recruiting now · Not applicable

Conditions studied: Cardiotoxicity

In brief

To test whether the implementation of new diagnostic techniques (ultrasonography, speckle tracking, vascular stiffness study, cardiac MRI, and histologic studies) allows in CAYA (Childern, Adolescents, and Young Adults) cancer survivors a more sensitive and earlier identification of cardiovascular damage resulting from antineoplastic therapy that develops either acutely or remotely after completion of antineoplastic therapy.

Key facts

Study ID

NCT07382141

Run by

IRCCS Azienda Ospedaliero-Universitaria di Bologna

People needed

400

Starts

2025-03-17

Expected to finish

2028-12-31

Last updated by the study team

2026-02-02

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of oncological pathology and need for antineoplastic treatment

You may not qualify if…

• None

Where it is running

• IRCCS - AOU di Bologna -Policlinico di Sant'Orsola UOC Pediatria — Bologna, Bologna, Italy (enrolling)
• IRCCS AOU di Bologna -Policlinico di Sant'Orsola UO Cardiochirurgia pediatrica e dell'età evolutiva — Bologna, Bologna, Italy (enrolling)
• IRCCS AOU di Bologna -Policlinico di Sant'Orsola UO Oncoematologia Pediatrica — Bologna, Bologna, Italy (enrolling)
• IRCCS AOU di Bologna Policlinico di Sant'Orsola UO Cardiologia Pediatria e dell'età evolutiva — Bologna, Bologna, Italy (enrolling)
• IRCCS AOU di Bologna Policlinico di Sant'Orsola UO Radiologia, sezione Cardio-Toraco-Vascolare — Bologna, Bologna, Italy (enrolling)

Full record on ClinicalTrials.gov

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