Strategy for Management of Patients With Hereditary Cancer Syndromes (HCS) in a Rural Environment
Enrolling by invitation · Not applicable
Conditions studied: Hereditary Cancer Syndromes, BRCA1 Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome
In brief
This study aims to improve cancer prevention and surveillance adherence in patients with Hereditary Cancer Syndromes (HCS), particularly those living in rural areas. The study will evaluate whether enrolling HCS patients in a longitudinal clinical program with individualized care plans and regular follow-up improves adherence to guideline-recommended cancer screening and risk-reduction strategies. Secondary aims include assessing the program's impact on patient distress and perceived care coordination. The study will enroll 200 adults with known pathogenic germline mutations who were previously seen at the UVM Medical Center genetics clinic. Participants will complete surveys at baseline, 12, and 24 months to assess adherence, distress, and care coordination. Findings from this study will inform future efforts to reduce gaps in hereditary cancer care delivery, especially for rural populations.
Key facts
- Study ID
- NCT07381985
- Run by
- University of Vermont Medical Center
- People needed
- 200
- Starts
- 2023-12-29
- Expected to finish
- 2027-12-01
- Last updated by the study team
- 2026-02-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients of all genders must be ≥ 18 years of age.
- Patients must have a known pathogenic germline variant in a cancer risk gene that was identified by a CLIA-approved lab more than one year ago.
- Patients must be able to accurately provide self-report data (i.e., per clinical judgment, cognitive function is intact).
- Patients must be able to complete questionnaires in English.
- Patients must have the ability to provide informed consent.
You may not qualify if…
- Patients who tested positive for a germline pathogenic variant associated with cancer risk < 1 year ago are not eligible.
Where it is running
- University of Vermont Medical Center — Burlington, Vermont, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.