GastroFlow: Investigation of the Gastrointestinal Blood Flow in Patients With Postprandial Hypotension
Enrolling by invitation · Not applicable · Has a placebo group
Conditions studied: Postprandial Hypotension, Healthy, Blood Flow
In brief
This project will describe the mechanisms of action and the relative contributions of GIP to changes in gastrointestinal blood flow induced by oral glucose and endogenous GIP with the use of a receptor antagonists GIP(3-30)NH2 in patients with postprandial hypotension.
Key facts
- Study ID
- NCT07381816
- Run by
- University of Copenhagen
- People needed
- 30
- Starts
- 2025-09-15
- Expected to finish
- 2027-05-01
- Last updated by the study team
- 2026-02-02
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Postprandial hypotension
- Symptoms of postprandial hypotension
You may not qualify if…
- Treatment with drugs that cannot be paused for 12 hours
- Metallic implants that does not tolerate MRI
- Any other disease or dysfunction that may disturb blood flow to the gut
- Intake of more than 14 units of alcohol per week or abuse of drugs
- Blood vessels that are not feasible for measuring flow in the MRI scanner
- Low blood percent
- Decreased kidney function
- Decreased liver function
- Claustrophobia
- For the healthy group
- Inclusion Criteria:
- Matched by age, gender and BMI
- Exclusion Criteria:
- Postprandial hypotension
- Metallic implants that does not tolerate MRI
- Intake of more than 14 units of alcohol per week or abuse of drugs
- Blood vessels that are not feasible for measuring flow in the MRI scanner
- Low blood percent
- Decreased kidney function
- Decreased liver function
- Claustrophobia
- Autonomic dysfunction or other disease that cause changes in blood pressure during or after a meal
- Intake of pharmaceutical products that influence the blood pressure
Where it is running
- Glostrup hospital — Glostrup Municipality, Denmark
Full record on ClinicalTrials.gov
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