Correlation of Oxygenation and Saturation Indices in One-Lung Ventilation
Starting soon
Conditions studied: One-lung Ventilation (OLV)
In brief
One-lung ventilation is commonly used during thoracic surgery but is frequently associated with impaired oxygenation and altered respiratory mechanics. Traditional oxygenation indices require arterial blood gas analysis and do not fully reflect the mechanical stress applied to the lungs. This prospective observational study aims to evaluate the correlation between oxygenation indices and oxygen saturation indices during one-lung ventilation in adult patients undergoing elective thoracic surgery. Modified indices incorporating driving pressure and mechanical power will also be assessed. No intervention beyond standard clinical care will be applied. The findings of this study may help clarify the clinical utility of non-invasive oxygenation indices for intraoperative monitoring during one-lung ventilation.
Key facts
- Study ID
- NCT07381517
- Run by
- Ankara Ataturk Sanatorium Training and Research Hospital
- People needed
- 51
- Starts
- 2026-02-09
- Expected to finish
- 2026-08-09
- Last updated by the study team
- 2026-02-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged 18 years and older
- Patients classified as ASA physical status I-III
- Patients scheduled for elective thoracic surgery requiring one-lung ventilation for at least 1 hour intraoperatively
- Patients in whom simultaneous arterial blood gas analysis and continuous SpO₂ monitoring can be performed
- Patients who have provided written informed consent
You may not qualify if…
- Patients undergoing emergency surgery
- Patients younger than 18 years of age
- Patients classified as ASA physical status IV or higher
- Patients with a history of previous thoracic surgery
- Patients with a body mass index (BMI) >40 kg/m² or <18 kg/m²
- Patients with advanced chronic lung disease (COPD stage III-IV)
- Patients with New York Heart Association (NYHA) class III-IV heart failure
- Patients undergoing surgery due to pleural effusion
Where it is running
- Ankara Ataturk Sanatoryum Education and Research Hospital — Ankara, Turkey (Türkiye)
Full record on ClinicalTrials.gov
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