Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat
Starting soon · Not applicable · Has a placebo group
Conditions studied: Postoperative Sore Throat
In brief
The aim of this study is to compare the efficacy of nebulized ketamine versus nebulized magnesium sulfate in reducing the incidence and severity of POST. * Primary outcome • To compare the incidence of POST method. * Secondary outcomes * Onset, Severity, and duration of POST at 0, 2, 4, 6, 12, 24 hours postoperative. * The hemodynamics recording (HR, BP, MBP, pre and post nebulization) * Adverse Effects (e.g., sedation, cough, nausea, vomiting, ….)
Key facts
- Study ID
- NCT07381036
- Run by
- Sohag University
- People needed
- 150
- Starts
- 2026-02-01
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2026-02-03
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age from 18 to 65 years old.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status I-II.
- Elective surgery requiring GA with endotracheal intubation.
- Exclusion Criteria:
- Surgery involves the oral cavity, nasopharynx, larynx, and neck regions.
- Surgery requires prone position.
- Surgery lasted more than 3 hours.
- History of preoperative sore throat, common cold.
- Anticipated difficult airway.
- Any known allergies to study drugs.
- Recent non-steroidal anti-inflammatory drugs use.
- Pregnancy.
Full record on ClinicalTrials.gov
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