The Effect of Functional Crown Lengthening Versus Deep Margin Elevation on Periodontal Tissues

Starting soon · Not applicable

Conditions studied: TNF Alpha

In brief

The present study will evaluate and compare the effect of functional CL and DME in the treatment of posterior teeth with class II caries clinically and on the level of TNF-α in the GCF of treated teeth. Clinical evaluation of periodontal tissue in the form of probing depth as a primary outcome, clinical attachment level, plaque index, bleeding index, gingival index, pink aesthetic score, Radiographic evaluation of biological width and the level of TNF-α in the GCF as a secondary outcome.

Key facts

Study ID

NCT07380126

Run by

Ain Shams University

People needed

20

Starts

2026-02-01

Expected to finish

2026-10-01

Last updated by the study team

2026-02-02

Who can join

Age: 20 and older, up to 50. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged 20-50 years
• Both genders
• Patients free from any systemic disease that may affect the treatment (Greenberg \& Glick, 2012)
• Patients with intact periodontium
• Patients are ready to comply with oral hygiene measures.
• Patients having Posterior teeth with carious cavities and/ or restorations in need of replacement on proximal surfaces, where the cervical margin of the cavity is at a distance less than 3 mm to the bone crest (Cyana et al.,2013).
• Patients with thick phenotype having gingival thickness > 1mm (Aimetti et al,2008).
• Patients with keratinized tissue width ≥ 2mm

You may not qualify if…

• Pregnant and lactating females
• Smokers
• Drug abusers.
• Patients with persistent poor oral hygiene
• Patients with proximal margins beyond the bone level
• Patients with developmental dental anomalies
• Patients undergoing or will start orthodontic treatment

Full record on ClinicalTrials.gov

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