Accuracy and Periodontal Outcomes of Three Interproximal Enamel Reduction Techniques During Clear Aligner Therapy

Starting soon · Not applicable

Conditions studied: Dental Crowding,Interproximal Enamel Reduction, Malocclusion, Angle's Class, Periodontal Diseases

In brief

This randomized controlled clinical trial will compare three commonly used interproximal enamel reduction (IPR) techniques during clear aligner therapy in adult patients. IPR is a routine orthodontic procedure in which a small amount of enamel is removed between teeth to create space and help achieve the planned alignment. Seventy-five adults (18 years and older) indicated for receiving clear aligner treatment with IPR prescribed in their digital treatment plan will be enrolled at the orthodontic clinics of Riyadh Elm University (Riyadh, Saudi Arabia) and randomized in a 1:1:1 ratio to one of three IPR techniques: manual abrasive strips (manual arm), motor-driven oscillating strips (motor-driven arm), or abrasive discs (abrasive arm). IPR will be performed by the same trained operator according to the assigned technique. The primary outcome is IPR accuracy, defined as the difference between the amount of IPR planned digitally and the amount performed clinically, measured using intraoral scans taken before and immediately after IPR. Secondary outcomes are short-term periodontal outcomes, assessed on IPR teeth only using plaque and gingival bleeding indices at baseline and at a 6-week follow-up visit. The data analyst will be blinded to group allocation

Key facts

Study ID

NCT07377825

Run by

Riyadh Elm University

People needed

75

Starts

2026-03-01

Expected to finish

2026-11-01

Last updated by the study team

2026-01-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years or older with full permanent dentition.
• Undergoing clear aligner therapy (Invisalign) with a ClinCheck treatment plan that includes interproximal enamel reduction (IPR).
• Periodontally healthy at baseline (per clinic screening).

You may not qualify if…

• Orthodontic treatment plan including extractions.
• Proximal restorations or caries on any tooth surface targeted for IPR.
• Current smoking.
• Diabetes mellitus or other systemic diseases known to affect periodontal status.

Where it is running

• Riyadh Elm University — Riyadh, Riyadh Region, Saudi Arabia

Full record on ClinicalTrials.gov

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