Combination Antibiotic Therapy for Staphylococcus Aureus Bacteremia

Starting soon · Phase 4

Conditions studied: Staphylococcus Aureus Bacteremia

In brief

The purpose of this study is to see if, in selected patients with a serious bacterial infection of the bloodstream, treating the bacterial infection with a combination of antibiotics is more effective than treating the infection with a single antibiotic. Participants must have blood cultures which are positive for a certain type of bacteria.

Key facts

Study ID

NCT07376889

Run by

Intermountain Health Care, Inc.

People needed

2096

Starts

2026-02-01

Expected to finish

2029-01-01

Last updated by the study team

2026-01-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years
• Alive and admitted to an Intermountain Health (IH) hospital acute care unit at enrollment
• Initial positive blood culture with either methicillin-resistant Staphylococcus aureus (MRSA) or methicillin-susceptible Staphylococcus aureus (MSSA), collected:
• on or during the index admission to an IH hospital, or
• in an ambulatory setting (laboratory, clinic or emergency department) within 48 hours of the index admission, or
• at a non-IH network hospital within 24 hours of subsequent transfer to an IH hospital

You may not qualify if…

• Patient requests that patient health data not be included in the analysis

Where it is running

• Platte Valley Hospital — Brighton, Colorado, United States
• Saint Joseph Hospital — Denver, Colorado, United States
• St. Mary's Regional Hospital — Grand Junction, Colorado, United States
• Good Samaritan Hospital — Lafayette, Colorado, United States
• Lutheran Medical Center — Wheat Ridge, Colorado, United States
• St. Vincent Regional Hospital — Billings, Montana, United States
• St. James Hospital — Butte, Montana, United States
• Holy Rosary Hospital — Miles City, Montana, United States
• Intermountain Medical Center — Murray, Utah, United States
• McKay-Dee Hospital — Ogden, Utah, United States
• Utah Valley Hospital — Provo, Utah, United States
• LDS Hospital — Salt Lake City, Utah, United States
• St. George Regional Hospital — St. George, Utah, United States

Full record on ClinicalTrials.gov

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