Molecular and Cellular Characterization of MALT Lymphoma

Starting soon

Conditions studied: MALT Lymphoma

In brief

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is an slow growing malignancy characterized by marked biological and clinical differences across different anatomical sites. Using participants' samples and clinical information, this observational and non-interventional research aims to generate a comprehensive molecular and cellular atlas of MALT lymphoma. The results will enable the identification of biologically meaningful tumor subtypes, microenvironmental niches, and candidate biomarkers with potential relevance for the diagnosis, prognosis, and therapy of MALT lymphoma.

Key facts

Study ID

NCT07376330

Run by

International Extranodal Lymphoma Study Group (IELSG)

People needed

400

Starts

2026-09-01

Expected to finish

2029-12-01

Last updated by the study team

2026-06-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female adults 18 years or older
• Diagnosis of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue on histology after Jan 1st, 2000.
• Availability of tumor material from biopsies (either frozen or formalin-fixed paraffin-embedded) (FFPE).
• Availability of the baseline and follow-up annotations.

You may not qualify if…

• None

Where it is running

• IRCCS Ospedale San Raffaele — Milan, Italy

Full record on ClinicalTrials.gov

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