Carotid Wall Texture as a Cardiovascular Risk Biomarker in Type 2 Diabetes Mellitus

Recruiting now

Conditions studied: Type 2 Diabetes Mellitus

In brief

This study aims to compare carotid intima-media thickness (CIMT) and layer-specific texture characteristics of the carotid wall between individuals with Type 2 diabetes mellitus (T2DM) and normoglycemic controls, to assess the impact of T2DM on these ultrasound variables and evaluate their ability to discriminate between low and high cardiovascular risk at 10 years.

Key facts

Study ID

NCT07373938

Run by

Cardenal Herrera University

People needed

80

Starts

2026-01-25

Expected to finish

2026-08-02

Last updated by the study team

2026-01-29

Who can join

Age: 40 and older, up to 69. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• European adults.
• Age between 40 and 69 years.
• Confirmed diagnosis of type 2 diabetes mellitus.
• No established cardiovascular disease.
• Availability of the required clinical and metabolic variables: Age; Sex; Systolic blood pressure; Non-high-density lipoprotein (non-HDL) cholesterol; Smoking status; Duration of diabetes; Glycated hemoglobin (HbA1c); Presence or absence of diabetes-related target organ damage (e.g., albuminuria, retinopathy)

You may not qualify if…

• History of clinical cardiovascular disease (secondary prevention).
• Type 1 diabetes mellitus.
• Patients with established severe target organ damage or conditions that automatically classify them as very high cardiovascular risk according to ESC guidelines.
• Advanced chronic kidney disease (estimated glomerular filtration rate <30 mL/min/1.73 m²).

Where it is running

• Francisco Javier Molina Payá — Elche, Alicante, Spain (enrolling)

Full record on ClinicalTrials.gov

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