Outcomes of Couples After Failed PGD Management: A Single-Center Study at the Paris PGD Center (Antoine Béclère - Necker)

Recruiting now

Conditions studied: Infertility

In brief

Preimplantation genetic testing (PGT) is a reproductive genetic technique aimed at preventing the transmission of severe genetic disorders. In France, its use is strictly regulated and reserved for complex medical situations, often associated with challenging reproductive histories and significant psychological burden. Despite scientific advances, success rates in preimplantation genetic testing remain limited, making the care pathway a significant source of uncertainty regarding the future of the parental project.

Key facts

Study ID

NCT07371312

Run by

Assistance Publique - Hôpitaux de Paris

People needed

900

Starts

2026-03-25

Expected to finish

2028-03-25

Last updated by the study team

2026-04-21

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Woman belonging to a couple who initiated at least one ovarian stimulation cycle for IVF (± ICSI) with preimplantation genetic diagnosis (PGD).
• No further PGD-related procedures (oocyte retrieval or embryo transfer) performed in the center after December 31, 2022.
• No live-born child resulting from PGD care.
• Woman who expressed her free and informed non-opposition to participation.

You may not qualify if…

• One or more live-born children resulting from PGD care in the center.
• PGD involving gamete donation.

Where it is running

• Hôpital Antoine Béclère — Clamart, France (enrolling)

Full record on ClinicalTrials.gov

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