Effect of Feedback-Based Balance Training on Balance and Gait in Cancer Patients With Chemotherapy-Induced Peripheral Neuropathy

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Conditions studied: Chemotherapy Induced Peripheral Neuropathy (CIPN)

In brief

Chemotherapy-induced peripheral neuropathy (CIPN) is a common complication of cancer treatment that can cause numbness, tingling, pain, balance problems, and difficulty walking. These symptoms may increase the risk of falls and reduce independence and quality of life in cancer survivors. The purpose of this study is to determine whether adding feedback-based balance training to conventional physiotherapy improves balance and walking ability in cancer patients with CIPN. Participants will be randomly assigned to one of two groups. One group will receive conventional physiotherapy along with feedback-based balance and gait training, while the other group will receive conventional physiotherapy alone. The intervention will be provided twice per week for four weeks. Balance, gait performance, neuropathy symptoms, and fear of falling will be assessed before and after the intervention using standardized clinical outcome measures. The findings of this study may help identify effective rehabilitation strategies to improve balance and mobility in cancer patients affected by chemotherapy-induced peripheral neuropathy.

Key facts

Study ID

NCT07368439

Run by

King Edward Medical University

People needed

70

Starts

2025-12-29

Expected to finish

2026-04-29

Last updated by the study team

2026-01-26

Who can join

Age: 30 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 30 to 60 years
• Diagnosed with breast, rectal, or stomach cancer
• History of treatment with neurotoxic chemotherapy
• Presence of chemotherapy-induced peripheral neuropathy as indicated by an EORTC CIPN20 total score of 24 or higher
• Ability to walk independently for at least 6 meters, with or without an assistive device
• Medically stable and able to participate in physiotherapy

You may not qualify if…

• Peripheral neuropathy due to causes other than chemotherapy (e.g., diabetes mellitus)
• History of neurological disorders affecting balance or gait (e.g., stroke, Parkinson's disease)
• Severe musculoskeletal conditions affecting balance or lower limb function
• Active foot ulcers, infections, or soft tissue injuries
• Severe visual impairment affecting balance
• Any medical condition that, in the investigator's judgment, would interfere with safe participation

Where it is running

• King Edward Medical University, Lahore — Lahore, Punjab Province, Pakistan

Full record on ClinicalTrials.gov

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