Diet Synergy in Muscle Protein Synthesis
Recruiting now · Not applicable
Conditions studied: Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis, Muscle Health, Protein Metabolism, Recreational Activities, Isotope Labeling
In brief
In the present semi-crossover randomized design, 15 recreationally active young adults (19-40 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise. Immediately after exercise, participants will ingest either 1 medium russet potato with skins and 2 ounce-equivalent lean ground beef combination (274 kcals, 19.3 g protein, 5 g fat, 37 g carbohydrates, and 4 g fiber), 2 slices of white bread and beef combination (262 kcals, 19.8 g protein, 6.8 g fat, 28 g carbohydrates, and 1.8 g fiber) or 2 ounce-equivalent beef (93% lean meat/7% fat; 110 kcals, 14.8 g protein, and 5 g fat). Repeated blood and muscle biopsies will be collected to determine whole body leucine kinetics, amino acid concentrations, anabolic signaling and myofibrillar protein synthesis rates during the trials.
Key facts
- Study ID
- NCT07367854
- Run by
- University of Illinois at Urbana-Champaign
- People needed
- 15
- Starts
- 2026-03-01
- Expected to finish
- 2028-11-01
- Last updated by the study team
- 2026-05-01
Who can join
Age: 19 and older, up to 40. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age 19-40 yrs
- Pre-menopausal
- Recreationally-active
- Weight stable for prior 6 months
You may not qualify if…
- Age outside of range (20 - 35 yrs)
- Pregnancy
- Irregular menstrual cycles (i.e., \~21 day or \~35 day cycle)
- Participation in previous research using L-[1-13C] leucine and L-[ring-2H5] phenylalanine
- Participation in other ongoing research that interferes with this study (e.g., conflicting diet, activity interventions, etc.)
Where it is running
- Louise Freer Hall — Urbana, Illinois, United States (enrolling)
- Louise Freer Hall — Urbana, Illinois, United States
Full record on ClinicalTrials.gov
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