Feasibility and Safety of Sciatic Nerve Paraneural Sheath Block Using a Mid-Femoral Lateral Approach
Starting soon · Not applicable
Conditions studied: Adverse Effect, Feasibility Study, Safety and Effectiveness
In brief
This study is designed as a randomized controlled trial aiming to evaluate the feasibility and safety of ultrasound-guided mid-femoral lateral approach sciatic nerve paraneural sheath block, in order to provide a new sciatic nerve block approach for clinical practice that offers greater patient comfort and higher precision, thereby facilitating its use for specific patient populations and less experienced operators.
Key facts
- Study ID
- NCT07366853
- Run by
- General Hospital of Ningxia Medical University
- People needed
- 200
- Starts
- 2026-01-01
- Expected to finish
- 2026-10-01
- Last updated by the study team
- 2026-01-26
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients scheduled for elective unilateral surgery below the knee (e.g., internal fixation for ankle, metatarsal, or calcaneal fractures; hallux valgus correction; flatfoot reconstruction).
- American Society of Anesthesiologists (ASA) physical status class I or II.
- Aged 18 to 65 years.
- Ability to understand the study procedure and provide written informed consent.
You may not qualify if…
- Contraindications to peripheral nerve block:
- Known allergy or history of toxicity to local anesthetics.
- Pre-existing neuropathy in the operative limb.
- Severe coagulopathy.
- Infection at the intended needle puncture site.
- Systemic infection.
- Requirement for simultaneous surgery at a site other than the unilateral lower limb below the knee.
- Previous surgery or significant scarring in the area of the planned needle insertion for the sciatic nerve block.
- Body mass index (BMI) > 35 kg/m².
- Patients receiving chronic pain therapy or with a history of opioid abuse.
- Inability to communicate or cooperate with the study assessments (e.g., due to cognitive impairment, language barrier, or psychiatric disorder).
- Pregnancy or lactation.
Where it is running
- General Hospital of Ningxia Medical University — Yinchuan, Ningxia, China
Full record on ClinicalTrials.gov
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