Beyond Observation: Validating the Ecological Relevance of the Ad-AHA Stroke Using Sensor-Based Measures

Recruiting now

Conditions studied: Stroke, Upper Limb Motor Impairment, Bimanual Function

In brief

After a stroke, many people experience difficulty using both hands together in daily life. Most rehabilitation assessments, however, only measure how the affected arm performs in one-handed tasks. This makes it difficult to understand how well people actually use their hands in real-world activities, which are usually bimanual. The Adult Assisting Hand Assessment - Stroke version (Ad-AHA Stroke) is a new clinical test that evaluates how the affected hand performs during two-handed tasks. While promising, it is still unknown whether the score on this test truly reflects how stroke survivors use their hands in daily life. This study aims to investigate this question by comparing Ad-AHA Stroke scores with real-life data on hand use, recorded over three days using wrist-worn sensors on both arms. By combining clinical and sensor-based measures, this study will help determine whether the Ad-AHA Stroke can accurately represent everyday bimanual performance after stroke.

Key facts

Study ID

NCT07366697

Run by

KU Leuven

People needed

32

Starts

2025-12-10

Expected to finish

2026-07-01

Last updated by the study team

2026-01-26

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Written informed consent obtained prior to any study procedures.
• Age between 18 and 80 years (inclusive).
• Unilateral supratentorial stroke involving cortical or subcortical structures.
• At least 6 months post-stroke at the time of inclusion.
• Community-dwelling (discharged from hospital and currently living at home).
• Able and willing to wear bilateral wrist-worn sensors (triaxial accelerometers) for three consecutive days.
• Presence of clinically observable bimanual impairment.

You may not qualify if…

• Severe upper limb impairment, defined as a Fugl-Meyer Assessment of Upper Extremity (FMA-UE) score ≤ 15.
• Severe cognitive or language comprehension impairment interfering with understanding of study instructions or task performance, as judged during screening.
• Presence of other neurological or orthopedic conditions affecting upper limb function (e.g., Parkinson's disease, multiple sclerosis, severe osteoarthritis, brachial plexus injury).

Where it is running

• Department of Rehabilitation Sciences, KU Leuven — Leuven, Belgium (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.