Clinical and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride, With or Without Application of LED, in Arresting Incipient Permament Molar Caries

Starting soon · Not applicable

Conditions studied: Incipient Caries

In brief

The study aims to compare the effect of international brand ammonia based 38% SDF, water based silver fluoride solution (AgF), an aqueous silver fluoride solution, and local brand ammonia based SDF with and without LED light application on caries arrest of initial enamel pits and fissure caries for permanent teeth of young adults

Key facts

Study ID

NCT07366645

Run by

Cairo University

People needed

366

Starts

2026-03-01

Expected to finish

2027-07-01

Last updated by the study team

2026-01-26

Who can join

Age: 18 and older, up to 25. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• high caries risk dental students
• Males or females
• Medically free
• Not taking medication
• At least had one active carious tooth
• Posterior permanent teeth
• ICDAS 2

You may not qualify if…

• non-Egyptian students
• Lack of compliance
• Allergic reaction to the materials used
• Pregnancy
• Dental students cannot give consent
• Teeth that will be extracted for orthodontic reasons
• Dental fluorosis
• Hypo calcified teeth
• Systemic diseases affecting teeth, such as amelogenesis imperfecta
• Severe periodontal affection

Full record on ClinicalTrials.gov

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