Comprehensive Analysis of the Swallowing Mechanism Using High-resolution Manometry With Impedance

Starting soon · Not applicable

Conditions studied: Extraesophageal Reflux, Laryngopharyngeal Reflux, Dysphagia, Chronic Cough

In brief

The aim of this project is to perform a detailed evaluation of upper esophageal sphincter function and the swallowing mechanism in patients with swallowing disorders or suspected extraesophageal reflux using high-resolution manometry with impedance and 24-hour pH-impedance monitoring.

Key facts

Study ID

NCT07365046

Run by

University Hospital Ostrava

People needed

160

Starts

2026-01-01

Expected to finish

2028-12-01

Last updated by the study team

2026-01-23

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age 18-75 years
• patients with swallowing difficulties suspected of having a functional oesophageal disorder or patients with clinical signs of extra-oesophageal reflux (Reflux Symptom Index [RSI] ≥ 13 or Reflux Symptom Score-12 [RSS-12] ≥ 11) signed informed consent

You may not qualify if…

• patients with a diagnosed tumor of the esophagus or upper airway, or with strong clinical suspicion of a tumor of the esophagus or upper airway
• severe neurological disease affecting swallowing
• pregnancy
• surgery involving the head, neck, or esophagus within the last 6 months

Where it is running

• University Hospital Ostrava — Ostrava, Moravian-Silesian Region, Czechia

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.