HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS

Recruiting now · Not applicable

Conditions studied: Geriatric Population, Spinal Anesthesia Induced Hypotension, Spinal Anesthesia in Elderly Patients

In brief

The goal of this clinical trial is to find out whether height-based dosing of spinal anaesthesia provides better hemodynamic stability and anesthetic outcome than conventional fixed dosing in elderly patients undergoing lower limb orthopaedic surgery.The main questions this study aims to answer are: 1. Does height-based spinal anaesthetic dosing reduce the risk of hypotension and bradycardia during surgery as compared to conventional fixed dosing? 2. Does it improve anaesthetic outcomes, such as the onset and duration of sensory and motor block?

Key facts

Study ID

NCT07363941

Run by

Shaheed Mohtarma Benazir Bhutto Institue of Trauma

People needed

104

Starts

2026-01-03

Expected to finish

2026-05-04

Last updated by the study team

2026-01-23

Who can join

Age: 60 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals aged 60 to 80 years. Either gender (male or female). Patients who are ASA physical status I-III. Individuals scheduled to undergo elective lower limb orthopaedic surgeries (e.g., fracture fixation, total knee replacement, open reduction and internal fixation).
• Patients planned to receive spinal anaesthesia as the primary anaesthetic technique.
• Those who provide informed written consent for participation in the study.

You may not qualify if…

• Individuals exhibiting a stature inferior to 150 cm. Patients receiving anti-hypertensive drugs or those on beta blockers or beta-agonists.
• Patients with a history of neurological disease like CVA or Parkinsonism. Patients presenting with sepsis (≥ 2 positive SIRS criteria with positive aseptically obtained blood or wound culture).
• Patients with a history of coagulation disorders like haemophilia or vWD or those with a history of anti-platelet drug intake in the last 2 weeks.
• Individuals possessing a documented history of hypersensitivity reactions to pharmacological agents utilized in the research.
• Patients who will be diagnosed with a skin infection at the spinal needle puncture site.
• Patients undergoing emergency orthopaedic procedures requiring immediate intervention

Where it is running

• Shaheed Mohtarma Benazir Bhutto Institue of Trauma — Karachi, Sindh, Pakistan (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.