Exploring the Effects of Hand and Foot Exercise Intervention in Older Adults With Gynecological Cancer Receiving Chemotherapy Improvement of Peripheral Neuropathy and Quality of Life
Starting soon · Not applicable
Conditions studied: Peripheral Neuropathy, Cervical Cancer, Endometrial Cancer, Ovarian Cancer, Vaginal Cancers, Fallopian Tube Cancers
In brief
Paclitaxel-based drugs are commonly used adjuvant chemotherapy for gynecological cancer patients. Peripheral neuropathy, a side effect of this treatment, presents with symptoms such as numbness, tingling, decreased skin and reflex sensation, and impaired function in the hands and feet, thus affecting quality of life. Peripheral neuropathy is a side effect caused by the neurotoxicity of certain chemotherapeutic drugs, including paclitaxel and platinum-based drugs, resulting from the cumulative toxicity of specific drug doses. While numerous international studies have confirmed the preventative effects of hand and foot movement interventions, there is a lack of relevant literature in China. Therefore, this study aims to explore the effects of hand and foot movement interventions on elderly gynecological cancer patients undergoing chemotherapy.
Key facts
- Study ID
- NCT07362147
- Run by
- Taipei Veterans General Hospital, Taiwan
- People needed
- 74
- Starts
- 2026-01-01
- Expected to finish
- 2027-11-30
- Last updated by the study team
- 2026-01-23
Who can join
Age: 65 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Individuals aged 65 or older diagnosed with gynecological cancer (stage II to IV) by a physician, without skin or nail lesions.
- Individuals who have received at least one course of chemotherapy within the past year and have peripheral neuropathy, with chemotherapy drugs including paclitaxel (Paclitaxel or Docetaxel) or platinum-based drugs (Cisplatin or Carboplatin), and may receive combined targeted or immunotherapy.
- Individuals who are conscious and able to communicate in Mandarin, Taiwanese, or written language.
You may not qualify if…
- Skin or nail lesions. Edema of 3+ or more in the extremities. History of diagnosis of diabetes, neuropathy, peripheral arterial ischemia, or multiple organ failure.
- Distal bone or skin metastases. Patients who have interrupted chemotherapy. Patients who have participated in similar studies.
Where it is running
- Taipei Veterans General Hospital — Taipei, No.201, Sec. 2, Shipai Rd., Beitou District, Taiwan
Full record on ClinicalTrials.gov
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