GLP1 Analogues and the Risk of Osteoarthritis

Starting soon

Conditions studied: Osteoarthritis

In brief

Assessing the effects of GLP1 RA Vs SGLT2 Inhibitors vs. Standard of care in joint pain, physical function, stiffness, and improving Quality of Life for patients with type 2 diabetes.

Key facts

Study ID

NCT07360457

Run by

Beni-Suef University

People needed

390

Starts

2026-02-01

Expected to finish

2027-03-01

Last updated by the study team

2026-01-22

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged above 50 years old with a previous diagnosis of T2DM according to ADA 2025, who have been on either SGLT2 inhibitors or GLP-1 analogs for at least one year.

You may not qualify if…

• individuals with Type 1 Diabetes Mellitus
• non-diabetic individuals
• those taking prandial insulin
• patients with arthritis without osteoarthritis,
• those taking other medications contraindicated with study medications,
• pregnant or breastfeeding females
• those allergic to active ingredients,
• those using corticosteroids, Autoimmune disease patients or patients receiving immunotherapies, monoclonal antibody targeting TNF-α or IL-6.

Full record on ClinicalTrials.gov

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