Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation
Recruiting now · Not applicable
Conditions studied: Gingival Pigmentation
In brief
To evaluate the usage of microneedling with platelet rich plasma as a gingival depigmentation method in comparison to microneedling alone for pigment intensity reduction. Pre-operative preparation phase includes ultrasonic scaling and oral hygiene instructions for all patients. Eligible patients will be randomly allocated into two groups. Clinical photographs: Clinical photographs will be taken at baseline, 1 and 6 months postoperatively. Intervention Group (Group A): Microneedling will be done with application of Platelet Rich Plasma for depigmentation. Control Group (Group B): microneedling will be done alone for depigmentation.
Key facts
- Study ID
- NCT07359339
- Run by
- Cairo University
- People needed
- 32
- Starts
- 2025-10-01
- Expected to finish
- 2026-11-10
- Last updated by the study team
- 2026-01-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- • Patients exhibiting melanin hyperpigmentation in the anterior region of the upper or lower gingiva.
- Age ≥ 18 year old.
- Patients should be free from any systemic diseases according to modified Cornell Medical index (Abramson 1966).
- Non- smokers
You may not qualify if…
- • Fully edentulous patients.
- Patients with endocrine disorders causing hyperpigmentation or drug induced gingival pigmentation. (Sreeja, Ramakrishnan et al. 2015)
- Pregnant or lactating females.
Where it is running
- Cairo university — Cairo, El Manial, Egypt (enrolling)
- Faculity of Dentistry, Cairo university — Cairo, El Manyl, Egypt (enrolling)
- Faculity of Dentistry, Cairo university — Cairo, El Manyl, Egypt (enrolling)
Full record on ClinicalTrials.gov
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