Eye-Brain-Kidney in CKD
Recruiting now
Conditions studied: Chronic Kidney Diseases
In brief
The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD). The main question it aims to answer is: Do changes in the brain's network connectivity and the retina's blood vessels correlate with cognitive decline and kidney function in CKD patients? Participants with CKD who are already undergoing clinical care will complete cognitive tests and questionnaires, have non-invasive MRI scans of their brain and kidneys, and undergo non-invasive eye imaging (OCT/OCTA) of their retinas.
Key facts
- Study ID
- NCT07358572
- Run by
- Beijing Friendship Hospital
- People needed
- 1500
- Starts
- 2025-12-01
- Expected to finish
- 2031-12-31
- Last updated by the study team
- 2026-01-27
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aged 18-70 years.
- Patients clinically diagnosed with CKD stages 1-5.
- No contraindications for MRI examination (e.g., cardiac pacemaker, claustrophobia, cochlear implant, hearing aid, coronary stents implanted before 2015) and able to complete the MRI scan.
You may not qualify if…
- Patients with recent or prior cerebral hemorrhage or cerebral infarction.
- History of epileptic seizures or psychiatric disorders.
- Patients with claustrophobia.
- Pregnant or lactating patients.
- Presence of other central nervous system diseases (e.g., tumor, trauma).
- Unstable angina, congestive heart failure (NYHA class III or IV), or acute myocardial infarction.
- Any systemic or other diseases deemed unsuitable for clinical trial participation.
Where it is running
- Beijing Friendship Hospital, Capital Medical University — Beijing, Beijing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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