Impact of Different Cardioplegia Solutions on Indicators of Myocardial Injury During Coronary Surgery

Starting soon · Not applicable

Conditions studied: Coronary Artery Bypass Grafting (CABG) Surgery, Myocardial Protection

In brief

The aim of the present study is to investigate intra-operative changes in markers of myocardial injury during ischemia and reperfusion, comparing three methods of myocardial protection; St. Thomas' cold crystalloid cardioplegia, Calafiore warm blood cardioplegia, or modified del Nido cold blood cardioplegia in routine coronary artery bypass grafting procedures.

Key facts

Study ID

NCT07358221

Run by

Damascus University

People needed

30

Starts

2026-02-01

Expected to finish

2027-02-01

Last updated by the study team

2026-01-22

Who can join

Age: 40 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All consecutive patients undergoing elective primary coronary artery bypass grafting will be enrolled in this study.

You may not qualify if…

• Patients will be excluded from this study if they had suffered from previous myocardial infarction, had reduced ejection fraction or were undergoing combined or repeated surgery

Where it is running

• Damascus University Cardiac Surgery Hospital — Damascus, Rif-dimashq Governorate, Syria

Full record on ClinicalTrials.gov

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