Oral Iron in Pregnant Women: How Often to Take It and Its Side Effects and Tolerability
Starting soon
Conditions studied: Iron Adverse Reaction, Anemia Complicating Pregnancy
In brief
The goal of this prospective observational study is to examine the frequency of gastrointestinal side effects associated with oral iron supplementation during pregnancy. The main question it aims to answer is: Does intermittent oral iron supplementation result in fewer gastrointestinal side effects compared with daily supplementation in pregnant women? Pregnant women who are prescribed oral iron as part of their routine medical care will take ferrous sulfate on an alternate-day schedule for one week. If no significant gastrointestinal side effects are reported, they will then take ferrous sulfate daily for an additional week and will be followed for one month. Participants will be contacted by the study investigator to report gastrointestinal side effects, and routine blood tests will be used to assess changes in hemoglobin and iron stores.
Key facts
- Study ID
- NCT07356258
- Run by
- Bnai Zion Medical Center
- People needed
- 50
- Starts
- 2026-02-01
- Expected to finish
- 2026-06-01
- Last updated by the study team
- 2026-01-27
Who can join
Age: 18 and older, up to 50. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Pregnant women aged 18-50
- Indication for oral iron treatment as determined by the treating physician, in accordance with standard clinical practice
- Baseline iron store levels measured prior to initiation of oral iron therapy
You may not qualify if…
- Women taking ferrous sulfate 80 mg Tardiferon
- Gastrointestinal diseases such as colitis
- Women who received intravenous iron during pregnancy
- Women who received blood transfusions during pregnancy
- Women with anemia due to causes other than iron deficiency
- History of bariatric surgery
- Allergy to ferrous sulfate
Where it is running
- Bnai Zion medical center — Haifa, Israel
Full record on ClinicalTrials.gov
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