Comparing Outcomes Of Single Layer Versus Multilayer Leg Closure Techniques Following Great Saphenous Vein Harvesting For CABG

Enrolling by invitation · Not applicable

Conditions studied: Surgical Wound Infection, Hematoma, Seroma Following Procedure, Prolonged Hospital Stay, Readmission Rates, Asepsis Score, Surgical Site Infection (SSI)

In brief

This study aims to address the knowledge gap by comparing the outcomes of single-layer and multi-layer leg closure techniques following great saphenous vein harvesting for Coronary artery bypass grafting. Research question: 1. Does single-layer closure compared to multi-layer closure result in better postoperative outcomes in patients undergoing great saphenous vein harvesting for CABG 2. To evaluate the incidence of postoperative complications (e.g., infection, hematoma, wound dehiscence, seroma) associated with single-layer vs. multi-layer closure techniques. participants will follow in OPD after 1 week , their wounds will be examined and assessment will be recorded.

Key facts

Study ID: NCT07355452
Run by: National Institute of Cardiovascular Diseases, Pakistan
People needed: 200
Starts: 2025-06-30
Expected to finish: 2026-03-30
Last updated by the study team: 2026-01-21

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

elective CABG
Both male and female patients
Patient of age between 18-70 years
Patients of consenting surgeons will be included in the study after elaboration of study protocol

You may not qualify if…

Patients with previous leg surgery,
peripheral vascular disease,
obesity, BMI; >30kg/m 2 .(weight in kilogram, height in meters)
varicose veins
those undergoing total arterial revascularization
emergency CABG

Where it is running

National Institute of cardiovascular diseases — Karachi, Sindh, Pakistan

Full record on ClinicalTrials.gov

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