Pelvic Nerve Mobilization for Primary Dysmenorrhea

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Primary Dysmenorrhea (PD)

In brief

Primary dysmenorrhea is a highly prevalent condition among young women and is associated with significant pain, reduced quality of life, and academic absenteeism. Although non-steroidal anti-inflammatory drugs are commonly used, many women seek non-pharmacological alternatives due to limited effectiveness or adverse effects. Emerging evidence suggests that altered pelvic neurodynamics may contribute to dysmenorrheic pain. This randomized controlled trial aims to evaluate the effectiveness of external pelvic nerve mobilization in reducing menstrual pain and associated symptoms among university women with primary dysmenorrhea. Participants aged 18-30 years will be randomly allocated to receive either external pelvic nerve mobilization or a sham manual therapy intervention across three consecutive menstrual cycles. Outcomes will include pain intensity, menstrual distress, quality of life, pelvic tenderness, analgesic consumption, and academic absenteeism.

Key facts

Study ID

NCT07354451

Run by

University of Hail

People needed

60

Starts

2025-10-20

Expected to finish

2026-07-30

Last updated by the study team

2026-04-29

Who can join

Age: 18 and older, up to 30. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Female university students aged 18-30 years
• Regular menstrual cycles (24-35 days)
• Clinically diagnosed primary dysmenorrhea
• Average menstrual pain intensity ≥ 5 on Visual Analog Scale
• Willingness to participate and provide informed consent

You may not qualify if…

• Secondary dysmenorrhea (e.g., endometriosis, fibroids, pelvic inflammatory disease)
• History of pelvic or spinal surgery
• Neurological disorders
• Current pregnancy or lactation
• Current physiotherapy or manual therapy treatment
• Contraindications to manual therapy

Where it is running

• International Institute of Science Arts and Technology — Sialkot, Pakistan (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.