Endoscopic Nipple-Sparing Mastectomy (E-NSM) With Immediate Multistage Autologous Fat Grafting(IMAFG) for Total Breast Reconstruction Via the Axillary Incision
Enrolling by invitation · Not applicable
Conditions studied: Breast Cancer, Breast Reconstruction
In brief
The goal of this clinical study is to evaluate the effectiveness and safety of a novel breast reconstruction technique combining endoscopic nipple-sparing mastectomy (E-NSM) with immediate multistage fat grafting (IMFG) in female patients aged 18 years or older with clinical stage 0 to II breast cancer who desire immediate breast reconstruction. The main questions it aims to answer are: Does the combined E-NSM and IMFG approach improve patient-reported outcomes, including satisfaction with breasts and physical well-being, as measured by the BREAST-Q questionnaire? What is the frequency and nature of surgical complications associated with this technique, such as wound healing, hemorrhage, and need for reoperation? Participants will undergo endoscopic nipple-sparing mastectomy with lymph node surgery followed by immediate multistage fat grafting for total breast reconstruction via a small cosmetic axillary incision. They will also complete the BREAST-Q questionnaire and receive clinical and photography-based assessments at follow-up visits to evaluate aesthetic and quality-of-life outcomes.
Key facts
- Study ID
- NCT07352137
- Run by
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- People needed
- 20
- Starts
- 2026-01-13
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-01-20
Who can join
Age: 18 and older, up to 70. Sex: female. Healthy volunteers: not accepted.
You may not qualify if…
- Breast cancer in pregnancy, tumours abutting the chest wall, skin (including inflammatory breast cancer), or nipple-areolar complex (NAC) (including Paget's disease), patients with breast cancer diagnosed as T3 or N2 and above, Allergic to lidocaine
Where it is running
- Guangdong Provincial Hospital Of Chinese Medicine — Guanzhou, Guangdong, China
Full record on ClinicalTrials.gov
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