Clinical, Microbial and Tissue-based Characterization of Patients Treated for Severe Temporomandibular Joint Pathology

Starting soon

Conditions studied: TMJ Disorder, Ankylosis, Osteoarthritis

In brief

The general objective of this observational study is to clarify the clinical, microbial, and tissue characteristics, aetiology, and risk factors behind severe TMJ pathology. The main questions it aims to answer are: * What are the clinical and histologic characteristics of patients with severe pathology of the TMJ? * Can microbial DNA be found in TMJ tissue from patients with severe pathology of the TMJ, and if so, does this correlate to the outcome of the surgery?

Key facts

Study ID

NCT07350239

Run by

Örebro University, Sweden

People needed

20

Starts

2026-03-01

Expected to finish

2029-02-01

Last updated by the study team

2026-01-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients subjected to open TMJ surgery such as arthroplastic surgery with or without autogen or allogen reconstruction
• Preserved biobank material (resected bone and soft tissue).

You may not qualify if…

• Absence of biobank material.
• Inability to give informed consent.

Full record on ClinicalTrials.gov

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