Comparison of Holmium, Thulium:YAG, and Thulium Fiber Lasers in Prostate Enucleation
Starting soon · Not applicable
Conditions studied: BPH (Benign Prostatic Hyperplasia)
In brief
Benign prostatic hyperplasia (BPH) is a common condition in aging men and may require surgical treatment when medical therapy is ineffective. Anatomical prostate enucleation using different laser technologies is a well-established surgical approach for the treatment of BPH. The purpose of this prospective randomized study is to compare the efficiency and safety of three commonly used laser systems-Holmium:YAG, Thulium:YAG, and Thulium Fiber Laser (TFL)-during anatomical prostate enucleation. The primary objective of the study is to evaluate laser efficiency by measuring grams of enucleated prostate tissue per joule (g/J) using intraoperative laser device data. Secondary outcomes include changes in International Prostate Symptom Score (IPSS) and the occurrence of postoperative urinary incontinence. All laser systems used in this study are part of routine clinical practice, and no additional diagnostic procedures or treatments will be performed for study purposes
Key facts
- Study ID
- NCT07350005
- Run by
- Ankara University
- People needed
- 159
- Starts
- 2026-05-01
- Expected to finish
- 2028-01-01
- Last updated by the study team
- 2026-01-20
Who can join
Age: 50 and older, up to 80. Sex: male. Healthy volunteers: not accepted.
You may qualify if…
- Patients diagnosed with benign prostatic hyperplasia (BPH) and scheduled for anatomical prostate enucleation
- Presence of a prostate and clinical indication for surgical treatment
- Age between 50 and 80 years
You may not qualify if…
- History or suspicion of prostate cancer
- Previous prostate surgery
- Presence of neurogenic bladder or significant lower urinary tract dysfunction unrelated to BPH
- Active urinary tract infection at the time of surgery
- Severe comorbid conditions contraindicating surgery or anesthesia
Where it is running
- Ankara University — Ankara, Turkey (Türkiye)
Full record on ClinicalTrials.gov
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