Automated Intraoperative Lung Recruitment Maneuvers in Major Laparoscopic Surgery

Recruiting now · Not applicable

Conditions studied: Atelectasis, Postoperative Pulmonary Complications (PPCs)

In brief

Laparoscopic colorectal surgery is associated with an increased risk of intraoperative atelectasis due to pneumoperitoneum, Trendelenburg positioning, and prolonged anesthesia duration. Atelectasis developing during surgery may persist into the postoperative period and contribute to postoperative pulmonary complications. Automated lung recruitment maneuvers delivered by modern anesthesia ventilators may offer a standardized method to improve lung aeration and reduce atelectasis. This prospective, randomized, single-center controlled trial aims to evaluate the effect of automated intraoperative lung recruitment maneuvers on atelectasis detected by lung ultrasonography in patients undergoing elective major laparoscopic colorectal cancer surgery. Adult patients will be randomized to receive either automated lung recruitment maneuvers or standard mechanical ventilation without recruitment. Lung ultrasonography will be used to assess atelectasis at predefined perioperative time points. The primary outcome is the incidence of atelectasis detected by lung ultrasound, and secondary outcomes include postoperative pulmonary complications, length of intensive care unit stay, length of hospital stay, and perioperative hemodynamic instability.

Key facts

Study ID

NCT07349784

Run by

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

People needed

56

Starts

2025-12-13

Expected to finish

2026-12-01

Last updated by the study team

2026-01-21

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 18 and 80 years
• Scheduled for elective laparoscopic colorectal cancer surgery
• American Society of Anesthesiologists (ASA) physical status I-III

You may not qualify if…

• ASA physical status IV or higher
• Pregnancy
• Body mass index (BMI) > 40 kg/m²
• Severe chronic obstructive pulmonary disease (COPD), GOLD stage III-IV
• Advanced heart failure with left ventricular ejection fraction <35%
• Previous thoracic surgery
• Preoperative requirement for supplemental oxygen therapy
• Refusal or inability to provide informed consent
• Intraoperative conversion to open surgery
• Development of significant hemodynamic instability during lung recruitment maneuvers

Where it is running

• SBÜ Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi — Istanbul, Bakırkoy, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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